R&D Researcher - Advanced in Boulder, CO at Volt

Date Posted: 1/1/2021

Job Snapshot

  • Employee Type:
  • Location:
    Boulder, CO
  • Duration:
    48 weeks
  • Date Posted:
  • Job ID:
  • Contact Name
    Volt Branch
  • Phone

Job Description

RNA Oligonucleotide Synthesis Chemist Research Associate – Boulder, CO

This company in Boulder, Colorado  which strives to power the growth through breakthrough science and technology is seeking a research associate to work with a team developing and scaling novel chemistries for RNA synthesis. Key responsibilities will be the production and purification of synthetic RNA and chemically modified synthetic RNA using automated solid-phase synthesis techniques. Other responsibilities will include sample preparation, data acquisition, and data analysis of synthetic oligonucleotides by LC-MS using Agilent QTOF instruments and software. Detailed recordkeeping of all steps in the workflow is imperative. You will be pushing RNA synthesis state of the art using Agilent's proprietary TC-RNA chemistry, and will be responsible for ordering, maintaining, and monitoring an inventory of chemical reagents, as well as maintenance and monitoring of the hardware components used for the synthesis, purification and analysis of the RNA products.

This company is the premier laboratory partner for a better world. We provide instruments, reagents and consumables, software and applications expertise to life science, diagnostic and applied market laboratories worldwide. 

Required Qualifications:

- MS/MA in Chemistry or Biochemistry, or equivalent.
- 2+ years' experience synthetic organic and/or analytical chemistry.
- Experience with HPLC purification techniques
- Experience with Mass Spectrometry.
- Practiced in the development and bottling of buffers and reagents, as well as the management of laboratory chemicals and raw materials inventories.
- Ability to work independently and to execute and troubleshoot new methods.
- Excellent time management, record keeping, teamwork and communication skills.
- Computer literacy including proficiency with Word and Excel

Desired Qualifications
- Experience in solid-phase oligonucleotide synthesis, using and trouble-shooting automated solid-phase synthesizers and optimizing synthetic protocols and reaction schemas.
- Experience in the optimization of purification protocols for oligonucleotides (RNA and DNA) via HPLC.
- Experience with Agilent Mass Hunter software for data acquisition and analysis
- Hands-on experience manipulating and synthesizing RNA in an R&D environment and practiced in anhydrous and RNAse-free lab techniques.

Volt is an Equal Opportunity Employer